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Sterone, also known as a steroid, is a type of organic compound that has a specific ring structure known as the steroid nucleus, which includes three six-membered rings and one five-membered ring. Steroids are broadly classified into different types based on their biological functions and structural features, such as sex hormones, adrenocortical hormones, and bile acids .
Estrone, specifically, is a natural estrogen hormone that belongs to the steroid family. It is an aromatized C18 steroid characterized by the presence of a 3-hydroxyl group and a 17-ketone. Estrone is synthesized in the body from androstenedion or testosteron through estradiol and is primarily produced in the ovaries, placenta, and peripheral tissues, notably adipose tissue. It is used in the management of perimenopausal and postmenopausal symptoms and is available under the brand name Estragyn, among others .
Steroid substances are known for their crucial roles in various biological processes. Estrone, for example, is involved in the development and maintenance of female reproductive tissues and secondary sexual characteristics. Additionally, it plays a role in bone health and lipid metabolism. Estrone has an estrogenic potency that is one third of that of estradiol .
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