| Customization: | Available |
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| CAS No.: | 2216-51-5 |
| Formula: | C10h20o |
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Natural menthol is a cyclic monoterpene alcohol derived primarily from peppermint (Mentha × piperita) or cornmint (Mentha arvensis) essential oils. It is the main bioactive compound responsible for the characteristic cooling sensation of mint plants.
Chemical Name: (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol
Molar Mass: 156.27 g/mol
Appearance: White crystalline solid with a strong minty odor
Melting Point: 41-43°C
Boiling Point: 212°C
Solubility:
Freely soluble in ethanol, ether, and chloroform
Slightly soluble in water (0.05% at 20°C)
Optical Rotation: -49° to -50° (indicating its natural L-form)
Extraction:
Obtained through freeze crystallization or vacuum distillation of peppermint/cornmint oil.
Cornmint oil typically contains 70-90% menthol, while peppermint oil has 30-50%.
Synthesis:
Can also be semi-synthetically produced from thymol or citral, but natural menthol is preferred in food/pharma applications.
Food & Beverage
Used as a flavoring agent in chewing gum, candies, toothpaste, and liqueurs.
GRAS (Generally Recognized as Safe) by the FDA (FEMA 2665).
Pharmaceuticals
Topical analgesic in muscle rubs, balms, and cold creams (e.g., Vicks VapoRub).
Relieves itchiness, sore throat, and nasal congestion (decongestant properties).
Cosmetics & Personal Care
Adds cooling effect in toothpaste, mouthwash, shaving creams, and lip balms.
Used in perfumery for fresh, minty notes.
Tobacco & Industrial Uses
Enhances cigarette and e-liquid flavors.
Acts as a pesticide synergist in agriculture
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