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Olanzapine is an atypical antipsychotic medication primarily used to treat schizophrenia and bipolar I disorder. It is available under various brand names, including Zyprexa, Zyprexa Zydis, Zyprexa Intramuscular, and Zyprexa Relprevv. The drug is known to work by blocking certain receptors in the brain, notably dopamine and serotonin, which helps in managing the symptoms of the aforementioned disorders. However, the exact mechanism of its action in these conditions is not fully understood.
Olanzapine is available in different dosage forms such as oral tablets, orally disintegrating tablets, intramuscular injections, and long-acting intramuscular injections. It was approved by the FDA on September 30, 1996, and generic versions are now available.
The typical starting dosage for adults with schizophrenia is 5 mg to 10 mg once a day, and for bipolar I disorder, it is 10 mg to 15 mg once a day. It is important to take olanzapine exactly as prescribed, and the dosage may be adjusted by the doctor until it is right for the individual.
Olanzapine can cause several side effects, some of which are serious. Common side effects include postural hypotension, constipation, weight gain, dizziness, sedation, headache, and dry mouth.
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