Customization: | Available |
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CAS No.: | 813-94-5 |
Formula: | N/a |
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Calcium citrate is a calcium salt that is commonly used as a dietary supplement to support bone health and is recognized for its superior absorption compared to other forms of calcium supplements, making it suitable for individuals with low stomach acid or those on acid-reducing medications . It is derived from citric acid and is available in various forms such as calcium citrate malate and calcium citrate tetrahydrate, with the chemical formula C12H10Ca3O14 and synonyms including tricalcium citrate .
Calcium citrate is known for its high bioavailability, which is important for the absorption of calcium from the intestines, and it can increase plasma calcium levels leading to a decrease in calcium flux and increase in calcium deposition into bone . It is utilized in pharmaceuticals, particularly in antacids and other medicinal formulations, due to these properties .
The global calcium citrate market is expanding due to growing awareness of its essential role in maintaining bone and tooth health, spurred by the increasing prevalence of lifestyle diseases and the health and wellness movement . The market size was valued at USD 852.3 million in 2022 and is predicted to grow at a 3.4% CAGR during the forecast period, driven by the rising use of calcium supplements among women, increased awareness of the importance of calcium, and demand from the sports and fitness industry .
Calcium citrate is also used in the treatment of osteoporosis and has been found to be effective in suppressing parathyroid hormone and bone resorption . It is considered a better calcium supplement than calcium carbonate in terms of bioavailability and has been studied for its effects on bone turnover in postmenopausal women .