| Customization: | Available |
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| CAS No.: | 22677-21-0 |
| Formula: | N/a |
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(R) 4-hydroxy-2-pyrrolidone, also known as (R) -4-hydroxy-2-pyrolidone with CAS number 22677-21-0, is an important organic compound. It has a wide range of applications in the fields of chemistry, medicine, and materials science. Especially in the pharmaceutical field, (R) -4-hydroxy-2-pyrrolidone plays a crucial role as a key intermediate in the preparation of Oxiracetam. Olacetam is a drug used to treat cerebrovascular diseases, belonging to the fourth generation of puzzle drugs, and is also a member of pyrrolidone derivatives.
In terms of chemical synthesis, (R) -4-hydroxy-2-pyrrolidone can be prepared by various methods, including chiral separation techniques and enzyme catalysis. Its physical and chemical properties include an optical rotation of alpha-23/D+43 ° (c=1 in ethanol), a melting point of 156-160 ° C, a boiling point of approximately 363.6 ± 35.0 ° C (predicted value), a density of 1.292 ± 0.06 g/cm3 (predicted value), and its solubility in water, DMSO, and methano is slightly soluble, slightly soluble, and slightly soluble, respectively.
In terms of safety data, (R) -4-hydroxy-2-pyrrolidone is classified as a substance that is irritating to the eyes and skin, and may have an impact on specific organ systems. Appropriate preventive measures need to be taken during handling and storage, such as wearing personal protective equipment, ensuring good ventilation conditions, avoiding contact with eyes and skin, and taking appropriate first aid measures in case of accidents.
Overall, (R) -4-hydroxy-2-pyrrolidone has attracted much attention due to its applications in the pharmaceutical field, and its synthesis method and safe use are also important aspects in research and industrial applications.
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