| Customization: | Available |
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| CAS No.: | 9003-97-8 |
| Formula: | (C20h18ca4o18)Mult |
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| Product names | Calcium polycarbophil |
| CAS No | 9003-97-8 |
Calcium polycarbophil is a synthetic polymer compound and CAS registry number 9003-97-8. It is a white, odorless powder that is insoluble in water. This compound is widely used in the pharmaceutical industry as an excipient in oral medications, particularly in the formulation of controlled-release tablets and capsules. It acts as a binder, stabilizer, and disintegrant, helping to improve the drug's bioavailability and release profile.
Calcium polycarbophil is also known for its high water-absorbing capacity, which makes it useful as a bulk-forming laxative to treat constipation. It is not absorbed from the intestine, does not interfere with digestive enzymes or intestinal absorption, and is physiologically inert. Additionally, it has been investigated for potential use in topical formulations for the treatment of skin disorders.
In pharmaceutical applications, calcium polycarbophil is used as a thickening agent at very low concentrations to produce a wide range of viscosities and flow properties in topical lotions, creams, and gels, as well as in oral suspensions and transdermal gel reservoirs. It is also an excellent bioadhesive in various mucosal applications, including buccal, ophthalmic, intestinal, nasal, vaginal, and rectal formulations.
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