| Customization: | Available |
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| CAS No.: | 13614-98-7 |
| Formula: | C23h28cln3o7 |
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| Product names | Minocycline hydrochloride |
| CAS No | 13614-98-7 |
Minocycline hydrochloride is a semi-synthetic derivative of tetracycline, belonging to the tetracycline class of antibiotics. It is widely used for its broad-spectrum antibacterial activity and other therapeutic properties.
Chemical Properties
Minocycline hydrochloride is a yellow crystalline powder. It is derived from minocycline, which contains two basic dimethylamino groups that readily form a salt with hydrochloric acid. This hydrochloride form is preferred for pharmaceutical applications.
Medical Applications
Antibacterial Activity: Minocycline hydrochloride is effective against a wide range of bacteria, including Gram-positive and Gram-negative organisms. It is particularly potent against staphylococci and streptococci, including some strains resistant to other antibiotics.
Anti-inflammatory Effects: It has been shown to inhibit inflammatory cytokines such as tumor necrosis factor (TNF-α) and matrix metalloproteinases (MMPs), making it useful in conditions involving inflammation.
Neuroprotective Properties: Minocycline hydrochloride has demonstrated neuroprotective effects, including reducing neuroinflammation and neuropathic pain.
Other Uses: It is also used to treat various infections, including respiratory tract infections, urinary tract infections, and acne.
Dosage Forms and Administration
Minocycline hydrochloride is available in various dosage forms, including capsules and tablets. Common strengths include 50 mg, 75 mg, and 100 mg capsules/tablets. It is typically administered orally and should be taken as directed by a healthcare provider.
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