Customization: | Available |
---|---|
Transport Package: | Drum |
Specification: | 99% |
Still deciding? Get samples of US$ 50/Piece
Request Sample
|
Suppliers with verified business licenses
Audited by an independent third-party inspection agency
Idebenone is a synthetic compound that is structurally similar to Coenzyme Q10, an essential component of the mitochondrial electron transport chain. It is known for its antioxidant properties and its ability to protect cells from oxidative damage. Idebenone is used in the treatment of certain neurological disorders, including Alzheimer's disease and Leber's hereditary optic neuropathy (LHON), and is being studied for its potential benefits in other conditions such as Friedreich's ataxia and Duchenne muscular dystrophy.
Idebenone functions as an antioxidant and may enhance mitochondrial function by increasing ATP production, reducing free radicals, and inhibiting lipid peroxidation. It is believed to transfer electrons directly to complex III of the mitochondrial electron transport chain, bypassing complex I, which can restore cellular energy (ATP) generation.
After oral administration, idebenone is rapidly absorbed, and its bioavailability is increased when taken with food. It can cross the blood-brain barrier and has been detected in the aqueous humor of the eye, indicating its potential for treating neurological and ophthalmological conditions.
Idebenone is generally well-tolerated, but side effects may include mild to moderate diarrhea, nasopharyngitis, cough, and back pain. Rarely, it may cause nausea, vomiting, stomach pain, and an increased risk of infection.