Idebenone CAS 58186-27-9 Health Care High Quality

Product Details
Customization: Available
Transport Package: Drum
Specification: 99%
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Management System Certification
ISO 9001
Export Year
2016-08-01
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  • Idebenone CAS 58186-27-9 Health Care High Quality
  • Idebenone CAS 58186-27-9 Health Care High Quality
  • Idebenone CAS 58186-27-9 Health Care High Quality
  • Idebenone CAS 58186-27-9 Health Care High Quality
  • Idebenone CAS 58186-27-9 Health Care High Quality
  • Idebenone CAS 58186-27-9 Health Care High Quality
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  • Overview
  • Product Description
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Overview

Basic Info.

Model NO.
58186-27-9
Origin
China
Production Capacity
10000kg/Month

Product Description

Product Description

 

Idebenone is a synthetic compound that is structurally similar to Coenzyme Q10, an essential component of the mitochondrial electron transport chain. It is known for its antioxidant properties and its ability to protect cells from oxidative damage. Idebenone is used in the treatment of certain neurological disorders, including Alzheimer's disease and Leber's hereditary optic neuropathy (LHON), and is being studied for its potential benefits in other conditions such as Friedreich's ataxia and Duchenne muscular dystrophy.

Mechanism of Action

Idebenone functions as an antioxidant and may enhance mitochondrial function by increasing ATP production, reducing free radicals, and inhibiting lipid peroxidation. It is believed to transfer electrons directly to complex III of the mitochondrial electron transport chain, bypassing complex I, which can restore cellular energy (ATP) generation.

Clinical Uses

  • Alzheimer's Disease: Idebenone may slow the decline of cognitive functions in patients with Alzheimer's disease, particularly in those with moderate to severe symptoms.
  • Leber's Hereditary Optic Neuropathy (LHON): It has been shown to improve vision in patients with LHON, especially if treatment is initiated early after the onset of vision loss.
  • Duchenne Muscular Dystrophy: Idebenone may improve respiratory function and slow the decline in patients with this type of muscular dystrophy.

Pharmacokinetics

After oral administration, idebenone is rapidly absorbed, and its bioavailability is increased when taken with food. It can cross the blood-brain barrier and has been detected in the aqueous humor of the eye, indicating its potential for treating neurological and ophthalmological conditions.

Side Effects

Idebenone is generally well-tolerated, but side effects may include mild to moderate diarrhea, nasopharyngitis, cough, and back pain. Rarely, it may cause nausea, vomiting, stomach pain, and an increased risk of infection.


 

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Idebenone CAS 58186-27-9 Health Care High Quality

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