| Customization: | Available |
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| Transport Package: | Drum |
| Specification: | 99% |
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Diethylene glycol monoethyl ether, also known as carbitol or DEGME, is a colorless liquid with a pleasant odor and is slightly viscous. It is soluble in water, alcohol, acetone, ether, carbon tetrachloride, and benzene. This compound has a melting point of approximately -78°C and a boiling point of around 195°C. It is used as a solvent for various applications, including in the pharmaceutical industry for drug delivery systems, in the cosmetics industry for creams and lotions, and in the paint and coating industry as a solvent and component in paint removers.
In the pharmaceutical industry, DEGME is recognized for its ability to enhance skin permeation, making it a valuable excipient in transdermal drug delivery systems. It is also used as a solvent for various pharmaceutical formulations due to its ability to dissolve a wide range of compounds.
Safety-wise, DEGME is considered to have low toxicity, with an LD50 value for rats of 5540 mg/kg when administered orally. However, it can cause central nervous system depression and respiratory damage in cases of excessive ingestion. It is also a skin and eye irritant, so proper handling and storage are recommended.
Diethylene glycol monoethyl ether is synthesized through chemical reactions involving ethylene oxide and ethanol. It is typically stored in glass bottles and should be kept away from heat and open flames due to its flammability.
In summary, diethylene glycol monoethyl ether is a versatile solvent with a wide range of industrial applications, particularly in the pharmaceutical and cosmetics sectors. It is important to handle this compound with care due to its potential health risks and to follow proper safety procedures.
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