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Specification: | 99% |
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Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate is a chemical compound with the CAS number 161798-01-2. It is also known by the name 2-(3-Formyl-4-hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid ethyl ester. This compound has a molecular formula of C14H13NO4S and a molecular weight of 291.32. It is a solid with a melting point of 116 °C and is soluble in DMSO and methanol. The compound is used as an intermediate in the synthesis of febuxostat, which is a medication used to treat gout by lowering uric acid levels in the blood. It is important to store this compound under inert gas (nitrogen or argon) at temperatures between 2-8°C to preserve its stability. In the laboratory, it is used as a non-purine selective inhibitor of xanthine oxidase, which is an enzyme involved in the metabolism of purines. The compound is also noted for its potential antimicrobial activity against Candida albicans.
In the pharmaceutical industry, this compound is used as an intermediate for the synthesis of febuxostat, which is a xanthine oxidase inhibitor indicated for the chronic management of hyperuricemia in adults . It is also used in the synthesis of other pharmaceuticals, contributing to the development of new drugs and therapies .
For more detailed information on its applications, including specific pharmaceutical uses, it is recommended to consult the latest scientific literature or contact suppliers and manufacturers who specialize in this compound