| Customization: | Available |
|---|---|
| Antibacterial Type: | Chemical Antibacterial, Natural Antibacterial |
| Applied animal classification: | Aquatic Animals, Livestock, Poultry |
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Specifications:
| ANALYSIS ITEM | SPECIFICATION | RESULT |
| Appearance | White crystalline powder | Conforms |
| Loss on drying | 10% Max | 5.4% |
| Arsenic Salt | 2ppm Max | Conforms |
| Heavy Metals | 20ppm Max | Conforms |
| Assay | 99.0% | 99.5% |
Mechanism of Action: Sodium sulfadiazine works by inhibiting bacterial growth through competitive antagonism of para-aminobenzoic acid (PABA), which is essential for the synthesis of folic acid in bacteria. This action disrupts the production of nucleic acids and proteins, ultimately leading to bacterial cell death.
Broad-Spectrum Antibacterial Activity: It is effective against a wide range of Gram-positive and Gram-negative bacteria. This includes pathogens responsible for various infections in animals, such as Streptococcus, Staphylococcus, and Escherichia coli.
Indications: Sodium sulfadiazine is primarily used to treat infections in dogs and cats, including urinary tract infections, skin infections, and respiratory infections. It is also used in livestock for treating bacterial infections and is effective against certain protozoan infections, such as those caused by Toxoplasma.
Pharmacokinetics: The drug is well absorbed when administered orally and can achieve therapeutic concentrations in the bloodstream. It has a relatively long half-life, allowing for less frequent dosing.
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