| Customization: | Available |
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| Transport Package: | Drum |
| Specification: | 99% |
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Topiramate is a medication primarily used to treat epilepsy and prevent migraines. It is available under various brand names such as Topamax, Qudexy XR, and Trokendi XR. Topiramate was initially approved by the FDA in 1996 and has since been prescribed for adults and children over 2 years of age for seizure control and for those over 12 years old for migraine prevention .
The drug's mechanism of action is not fully understood, but it is known to affect certain chemicals in the brain that are involved in seizures and migraines. Topiramate is thought to enhance the activity of GABA, an inhibitory neurotransmitter, and to modulate the activity of glutamate, an excitatory neurotransmitter. It also inhibits carbonic anhydrase, which may contribute to its efficacy in treating seizures and migraines .
Topiramate is available in immediate-release and extended-release formulations. It can be taken with or without food, and it is important to follow the prescribed dosage and schedule. The medication is usually started at a low dose and gradually increased to minimize side effects. It is eliminated from the body primarily through the kidneys .
Common side effects of topiramate can include dizziness, drowsiness, confusion, and problems with memory or speech. More serious side effects can include mood changes, suicidal thoughts, metabolic acidosis, kidney stones, and eye disorders such as glaucoma or cataracts. Patients are advised to report any new or worsening symptoms to their healthcare provider
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