| Customization: | Available |
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| CAS No.: | 73963-72-1 |
| Formula: | N/a |
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Cilostazol, with the CAS number 73963-72-1, is a pharmaceutical compound belonging to the class of phosphodiesterase inhibitors, specifically a PDE3 inhibitor. It is a white or almost white crystalline powder, practically insoluble in water, and has a molecular formula of C20H27N5O2, with a molecular weight of 369.46 .
Cilostazol is primarily used for its antiplatelet and vasodilatory effects. It functions by inhibiting phosphodiesterase enzymes in platelets and vascular smooth muscle cells, leading to an increase in cAMP levels, which in turn inhibits platelet aggregation and promotes vasodilation . This results in improved blood flow, particularly in conditions characterized by arterial obstruction such as chronic arterial occlusion, intermittent claudication, and peripheral artery disease .
The drug is typically administered orally, with the usual dose being 100 mg twice daily. It is available in the form of tablets or capsules for oral ingestion. Cilostazol is widely used in clinical practice for the treatment of symptoms associated with chronic arterial circulatory disorders, including pain, ulcers, and cold sensations in the extremities .
Cilostazol has been the subject of numerous clinical trials, demonstrating its efficacy in improving walking distance and reducing symptoms in patients with intermittent claudication
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