| Customization: | Available |
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| CAS No.: | 144689-63-4 |
| Formula: | C29h30n6o6 |
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Product name: Olmesartan Medoxomil
CAS No: 144689-63-4
Olmesartan medoxomil is an angiotensin II receptor antagonist (ARB), used primarily for the treatment of hypertension (high blood pressure). It is a prodrug that is converted to its active form, olmesartan, after absorption in the body. Olmesartan works by blocking the binding of angiotensin II, a hormone that constricts blood vessels and increases blood pressure, to its receptors (AT1). This results in vasodilation (relaxation of blood vessels), lowering blood pressure and improving blood flow.
Application and Effect
Olmesartan medoxomil is primarily prescribed for the treatment of hypertension, either as a monotherapy or in combination with other antihypertensive drugs. By blocking the action of angiotensin II, olmesartan helps to relax blood vessels, thereby reducing blood pressure. This leads to a decreased risk of heart failure, stroke, and kidney damage, conditions often associated with prolonged high blood pressure. In addition to its primary use in managing high blood pressure, olmesartan has also been studied for its potential benefits in protecting the kidneys from damage caused by diabetes and high blood pressure. It helps prevent kidney damage by reducing the effects of angiotensin II, which can constrict the blood vessels in the kidneys and impair their function. This makes olmesartan particularly beneficial for patients with both hypertension and diabetic nephropathy. Olmesartan medoxomil is typically well tolerated, with side effects being relatively mild. The most common adverse effects include dizziness, headache, and gastrointestinal discomfort. Like other ARBs, olmesartan does not generally cause the dry cough associated with angiotensin-converting enzyme (ACE) inhibitors, making it a preferable option for patients who experience such side effects. However, it should be used cautiously in patients with renal impairment, and regular monitoring of kidney function is recommended.
Specifications:
| Composition | C29H30N6O6 |
| Assay | 99% |
| Appearance | White to beige powder |
| CAS No. | 144689-63-4 |
| Packing | Small and bulk |
| Shelf Life | 2 years |
| Storage | Store in cool and dry area |
| Certification | ISO. |
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