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CAS No: | 78628-80-5 |
Transport Package: | Bag Drum Box |
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Product name: Terbinafine Hydrochloride
CAS No: 78628-80-5
Terbinafine Hydrochloride is an antifungal agent with a specific chemical structure. It belongs to the allylamine class of antifungal drugs. Its molecular formula is C21H26ClN, and this structure enables it to interact with a key enzyme involved in fungal cell membrane synthesis, thereby exerting its antifungal effects.
Application and Effect
Terbinafine Hydrochloride is widely used for the treatment of various fungal infections. It is particularly effective against dermatophytes, which are fungi that commonly infect the skin, hair, and nails. In cases of tinea pedis (athlete's foot), tinea corporis (ringworm of the body), tinea cruris (jock itch), and onychomycosis (fungal nail infections), it has shown excellent efficacy.
The way it works is by inhibiting the enzyme squalene epoxidase. Fungi rely on this enzyme to synthesize ergosterol, a crucial component of their cell membranes. By blocking this enzyme, Terbinafine Hydrochloride disrupts the synthesis of ergosterol, leading to an abnormal cell membrane structure in the fungi. This, in turn, causes the fungal cells to leak vital substances and eventually die.
It is generally well-tolerated by patients, although some side effects may occur. Common side effects include mild gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal pain. In some cases, there may also be skin rashes or itching. However, these side effects are usually mild and can often be managed with appropriate medical advice.
Overall, Terbinafine Hydrochloride is a highly effective antifungal drug that has significantly improved the treatment options for fungal infections, especially those affecting the skin, hair, and nails.
Specifications:
Composition | C21H26ClN |
Assay | 99% |
Appearance | white powder |
CAS No. | 78628-80-5 |
Packing | Small and bulk |
Shelf Life | 2 years |
Storage | Store in cool and dry area |
Certification | ISO. |