| Customization: | Available |
|---|---|
| Antibacterial Type: | Chemical Antibacterial, Natural Antibacterial |
| Applied animal classification: | Aquatic Animals, Livestock, Poultry |
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Specifications:
| ANALYSIS ITEM | SPECIFICATION | RESULT |
| Appearance | white powder | Conforms |
| Loss on drying | 10% Max | 5.4% |
| Arsenic Salt | 2ppm Max | Conforms |
| Heavy Metals | 20ppm Max | Conforms |
| Assay | 99.0% | 99.5% |
Mechanism of Action: Maduramicin ammonium inhibits the growth of coccidia by disrupting the transport of ions across their cell membranes, which leads to an imbalance in the osmotic pressure and ultimately causes the cells to burst .
Usage in Poultry: It is commonly added to poultry feed at a concentration of 5 mg/kg to prevent coccidiosis, a disease caused by protozoan parasites of the genus Eimeria. The withdrawal period before slaughter is typically 5-7 days .
Toxicity: Maduramicin ammonium can be toxic to non-target animals such as cattle, sheep, and pigs if they consume feed containing this drug or litter contaminated with it. It has been associated with skeletal muscle and heart cell damage, leading to muscle degeneration and heart failure .
Regulatory Considerations: In some countries, the use of maduramicin ammonium is regulated, with specific guidelines on its inclusion in animal feed and withdrawal periods to ensure that residues in meat products are within safe limits
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