| Customization: | Available |
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| CAS No.: | 123536-14-1 |
| Formula: | N/a |
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(R)-3-Aminoquinuclidine dihydrochloride is a chiral compound often used as an intermediate in the synthesis of various pharmaceuticals. It is a derivative of quinuclidine, a heterocyclic compound with potential applications in the development of drugs targeting the nervous system. The dihydrochloride salt form of this compound enhances its solubility, which is a common practice in pharmaceutical chemistry to improve the delivery and absorption of drugs.
This compound is particularly significant in the synthesis of certain muscarinic agonists and antagonists, which can be used to treat a variety of conditions such as glaucoma, urinary incontinence, and overactive bladder. The (R)-enantiomer is often preferred due to its specific biological activity, which can differ significantly from its (S)-counterpart.
In the context of medicinal chemistry, the enantiomeric purity of such compounds is crucial as it can directly affect the efficacy and safety of the final drug product. The dihydrochloride salt form aids in the stability and handling of the compound during the synthesis process.
It is important to note that while (R)-3-Aminoquinuclidine dihydrochloride is a valuable synthetic intermediate, the final drug products and their applications are subject to rigorous testing and regulatory approval before they can be used in clinical settings. The use of such intermediates is a critical aspect of the drug discovery and development process.
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