Customization: | Available |
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CAS No.: | 282526-98-1 |
Formula: | N/a |
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Cetilistat, with the CAS number 282526-98-1, is a potent and long-acting inhibitor of pancreatic lipase, which is being developed for the treatment of obesity and associated co-morbidities, such as type 2 diabetes. It operates by inhibiting the enzyme pancreatic lipase, thus reducing the digestion and absorption of dietary fats. This leads to a decrease in caloric intake and subsequent weight loss .
Cetilistat, also known by the developmental code name ATL-962, has been shown to reduce body weight gain and improve lipid profiles in preclinical studies . It is a white crystalline powder with a molecular formula of C25H39NO3 and a molecular weight of 401.58. The compound is poorly soluble in water but has good solubility in ethanol. It is typically stored at -20°C for long-term preservation and is stable for up to three years when stored properly .
In clinical trials, Cetilistat has been investigated for its efficacy and safety in obese patients. It has shown promise in reducing fat absorption and aiding in weight management when used in conjunction with a reduced-calorie diet . The drug is usually administered orally and has been well-tolerated in clinical studies, with the most common side effects being mild gastrointestinal symptoms