Diethyl Malonate CAS 105-53-3 Health Care High Quality

• Customization: Available
• Transport Package: Drum
• Specification: 99%
• Model NO.: 105-53-3
• Trademark: PUYER
• Origin: China
• Production Capacity: 10000kg/Month

Product Description

Product Description

 

Diethyl malonate, with the chemical formula C7H12O4 and the CAS number 105-53-3, is an organic compound that is a colorless liquid with a sweet, ethereal odor. It is soluble in alcohol, ether, and most organic solvents, but only slightly soluble in water. Diethyl malonate has a melting point of approximately -50°C and a boiling point of around 199.3°C. It is used as an organic synthesis intermediate and can be found in the production of various pharmaceuticals, fragrances, and dyes.

Chemical Properties:

• Diethyl malonate is a diester of malonic acid and is known for its reactivity due to the presence of two ester groups.
• It can undergo hydrolysis to form malonic acid and ethanol.
• The compound is also capable of participating in various organic reactions, such as condensation and substitution reactions, making it a valuable building block in organic synthesis.

Applications:

• It serves as an intermediate in the synthesis of pharmaceuticals like sulfonamides and barbiturates.
• Diethyl malonate is used in the preparation of 2-amino-4,6-dimethoxypyrimidine, which is an important intermediate for the synthesis of sulfonylurea herbicides.
• It is also utilized in the production of fragrances and as a solvent for resins and nitrocellulose.
• Additionally, it is listed as an allowed food flavoring agent in some regulations, primarily for creating fruit flavors such as pear, apple, grape, and cherry.

Safety Information:

• Diethyl malonate is considered to have low toxicity, with a rat oral LD50 of greater than 1600 mg/kg.
• However, it can hydrolyze in the body to form acid, so it is important to avoid contact and to wash thoroughly if contact occurs.
• Safety measures include wearing rubber gloves and using proper ventilation to handle this substance.

 

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