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Transport Package: | Cartons/Drums |
Specification: | white tablet |
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N-Acetyl-L-arginine (NALA) is an organic compound that belongs to the class of n-acyl-l-alpha-amino acids, characterized by the presence of an acetyl group attached to the alpha-amino nitrogen of the L-arginine . This compound is known to have a molecular weight of approximately 216.24 and a molecular formula of C8H16N4O3. It is recognized for its strong basic nature due to its pKa value and is found in various biological contexts, including in the serum of patients with certain conditions such as hyperargininemia .
NALA has been identified in the serum of pediatric patients with hemodialysis renal insufficiency and is associated with the inborn metabolic disorder hyperargininemia. It has also been linked to conditions like uremia and colorectal cancer . In the context of biopharmaceuticals, N-Acetyl-L-arginine has been studied for its potential as a protein aggregation suppressor, especially under conditions of interfacial stress and elevated temperatures, which is crucial for the stability of protein liquid formulations .
Furthermore, N-Acetyl-L-arginine can be used as a research tool or for drug certification applications, but it is not intended for human consumption or medical treatment. It is available in various purities and packaging options for scientific research purposes . When it comes to storage, solid N-Acetyl-L-arginine should be kept at -20°C for long-term preservation, while solutions should be stored at -80°C . For solubility, it is recommended to use DMSO as a solvent, with sonication to assist in dissolving the compound .