Customization: | Available |
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CAS No.: | 633-65-8 |
Formula: | N/a |
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Berberine hydrochloride, with the CAS number 633-65-8, is a natural quaternary ammonium salt compound extracted from plants such as Coptis chinensis Franch, Berberis vulgaris, and Hydrastis canadensis. It is known for its wide range of pharmacological activities, including antimicrobial, anti-inflammatory, and antidiabetic effects .
This yellow crystalline powder is soluble in water and has a molecular formula of C20H18ClNO4. Berberine hydrochloride is commonly used in traditional medicines for its ability to target a variety of diseases, such as bacterial dysentery, diarrhea, and gastroenteritis .
Pharmacologically, Berberine hydrochloride has demonstrated the ability to modulate various biological processes. It influences glucose and lipid metabolism, which has led to its investigation as a potential therapeutic agent for diabetes and hyperlipidemia. Research also shows that it may have beneficial effects on cardiovascular health by improving endothelial function and reducing inflammation .
In terms of safety, Berberine hydrochloride is generally considered non-toxic, but it may cause gastrointestinal upset in some individuals. It should be used with caution by pregnant and breastfeeding women, and those with known hypersensitivity to the compound should avoid it