| Customization: | Available |
|---|---|
| Antibacterial Type: | Chemical Antibacterial, Natural Antibacterial |
| Applied animal classification: | Aquatic Animals, Livestock, Poultry |
|
Still deciding? Get samples of US$ 1/kg
Request Sample
|
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
Specifications:
| ANALYSIS ITEM | SPECIFICATION | RESULT |
| Appearance | White crystalline powder | Conforms |
| Loss on drying | 10% Max | 5.4% |
| Arsenic Salt | 2ppm Max | Conforms |
| Heavy Metals | 20ppm Max | Conforms |
| Assay | 99.0% | 99.5% |
Maduramicin is a polyether ionophore antibiotic that has been found in Nocardia species. It selectively binds to potassium, rubidium, sodium, lithium, and cesium ions over divalent cations. Maduramicin exhibits activity against Gram-positive bacteria with MICs ranging from 0.9 to 125 µg/ml, but it is not active against Gram-negative bacteria (MICs >1,000 µg/ml) or fungi (MICs 250->1,000 µg/ml) .
In the veterinary field, Maduramicin is used as an anticoccidial drug to treat coccidiosis in chickens. It is effective in reducing the severity of lesions and protecting chicks against mortality in a model of coccidiosis induced by E. tenella. Formulations containing Maduramicin are administered at 5-10 ppm in the diet .
Recent research has discovered that Maduramicin can also act as a novel glycosylation modulator for mammalian fed-batch and steady-state perfusion processes. It has been found to selectively increase M5 glycans of monoclonal antibody (mAb) products. This discovery expands the current glycosylation modulating toolbox for biotherapeutics, making Maduramicin a universal tool for both fed-batch and continuous manufacturing processes.
){kind=link}