Customization: | Available |
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CAS No.: | 113-24-6 |
Formula: | N/a |
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Sodium pyruvate (CAS 113-24-6) is a vital compound in human metabolism and nutrition, playing a significant role in energy production and various biological processes. It is a three-carbon ketoacid that is naturally produced during glycolysis, the metabolic pathway that breaks down glucose to generate energy. Here are some key points about its applications and benefits:
Energy Metabolism: Pyruvate is a crucial molecule in the Krebs cycle (citric acid cycle), which is the series of chemical reactions that produce energy in the form of ATP. It is also involved in the conversion of glucose to energy, making it an essential component of cellular respiration.
Antioxidant Activity: Pyruvate has been shown to exhibit antioxidant properties, which can help protect cells from damage caused by free radicals. It can also influence the cellular redox state, which is important for maintaining proper cellular function.
Supplementation: While early studies suggested that pyruvate supplementation could have ergogenic effects, more recent and well-controlled studies have shown that supplementation for more than a week does not provide significant benefits for physically active individuals. However, it is still used as a dietary supplement for its potential to support energy production and metabolic health.
Medical Applications: Sodium pyruvate has been studied for its potential therapeutic effects in various conditions, including diabetes and its complications, heart failure, and liver cirrhosis. It has also been investigated for its potential role in treating mitochondrial diseases due to its ability to improve cellular energy metabolism.
Cell Viability and Aging: Research indicates that pyruvate may play a role in maintaining cell viability and energy production, particularly under conditions of high glucose. It has been suggested that pyruvate could be advantageous in preventing and treating diseases and aging, possibly through its effects on NAD+ homeostasis and as a senolytic agent.