Customization: | Available |
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Transport Package: | Drum |
Specification: | 99% |
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Dapagliflozin propanediol, also known as Dapagliflozin, is an orally active medication that belongs to the class of sodium-glucose cotransporter 2 (SGLT2) inhibitors. It is primarily used for the management of type 2 diabetes mellitus. Dapagliflozin works by inhibiting the SGLT2 in the kidneys, which results in the reduction of glucose reabsorption and an increase in urinary glucose excretion, thereby lowering blood glucose levels. This medication is often used in conjunction with diet and exercise to improve glycemic control in adults with type 2 diabetes.
Dapagliflozin has been studied for its potential benefits beyond glycemic control, including weight loss and blood pressure reduction, due to the increased urinary excretion of glucose, sodium, and water. It has also been investigated for its potential to reduce the risk of kidney function decline, kidney failure, cardiovascular death, and hospitalization for heart failure in adults with chronic kidney disease.
The drug is generally well-tolerated, but it can cause side effects such as urinary tract infections, genital mycotic infections, and in some cases, an increased risk of diabetic ketoacidosis. It is important to monitor for these potential side effects during treatment.
Dapagliflozin is available in various formulations, including as a single ingredient or in combination with other antidiabetic drugs like metformin hydrochloride. It is approved for use in many countries, including the United States and various European countries, and is marketed under brand names such as Farxiga and Xigduo, among others.