| Customization: | Available |
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| CAS No.: | 209995-38-0 |
| Formula: | N/a |
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2,4,5-Trifluorophenylacetic acid, with the CAS number 209995-38-0, is a fine chemical known for its application in the synthesis of pharmaceuticals, particularly as an intermediate for the anti-diabetic drug sitagliptin. This compound is part of the class of fluorophenylacetic acids and is characterized by the presence of three fluorine atoms on the benzene ring.
Chemical Properties:
Uses: It is utilized in the synthesis of sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor used for treating type 2 diabetes. The compound is also used as a bifunctional additive for perovskite solar cells, enhancing their power conversion efficiency and stability.
Manufacturing Process: The synthesis of 2,4,5-trifluorophenylacetic acid involves a multi-step process, starting with the preparation of 2,4,5-trifluorobenzyl magnesium chloride and followed by reactions with dry ice to produce the final product. The crude product is then recrystallized for purification.
Safety Information: As a chemical intermediate, it is essential to handle 2,4,5-trifluorophenylacetic acid with care, adhering to proper safety measures and regulations. It is classified as an irritant and has specific hazard codes associated with its use.
For detailed safety data, including handling, storage, and disposal, refer to the material safety data sheet (MSDS) provided by the manufacturer.
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