| Customization: | Available |
|---|---|
| CAS No.: | 19608-29-8 |
| Formula: | N/a |
|
Still deciding? Get samples of $ !
Request Sample
|
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
Clascoterone, with the CAS number 19608-29-8, is a pharmaceutical compound that has been developed for the treatment of acne vulgaris. It is a potent topical antiandrogen, which means it acts locally on the skin to counter the effects of androgens that contribute to acne. This agent is significant because it offers a novel mechanism of action compared to other acne treatments, potentially providing a more targeted approach to managing the condition.
Clascoterone is approved by the U.S. Food and Drug Administration (FDA) for use in patients aged 12 and older. It is supplied as a 1% cream under the brand name Winlevi, with each gram of cream containing 10 mg of the active substance. The cream is intended for twice-daily application on clean, dry skin and should be used according to a physician's instructions. It is reported to be well-tolerated, with common side effects including local skin reactions such as redness, dryness, and itching .
The compound is a white to light yellow powder with a molecular formula of C24H34O5 and a molecular weight of 402.52. It is poorly soluble in water but dissolves in dimethyl sulfoxide (DMSO). The chemical structure of Clascoterone features a pregnene framework with a 21-hydroxyl group and a 17-(1-oxopropoxy) group, which contributes to its biological activity
){kind=link}