Customization: | Available |
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Antibacterial Type: | Chemical Antibacterial, Natural Antibacterial |
Applied animal classification: | Aquatic Animals, Livestock, Poultry |
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Specifications:
ANALYSIS ITEM | SPECIFICATION | RESULT |
Appearance | white or light yellow powder | Conforms |
Loss on drying | 10% Max | 5.4% |
Arsenic Salt | 2ppm Max | Conforms |
Heavy Metals | 20ppm Max | Conforms |
Assay | 99.0% | 99.5% |
Antibacterial Activity: Diaveridine exhibits in vitro antibacterial efficacy against a range of Gram-negative and Gram-positive bacteria, such as Escherichia coli, Clostridium spp., Salmonella spp., Staphylococcus aureus, and Bacillus anthracis .
Anticoccidial Effect: It has significant activity against coccidia and other protozoa, making it useful in the prevention and treatment of coccidiosis in poultry and rabbits .
Combination Therapy: Diaveridine is often used in combination with sulfonamides like sulfaguanidine and sulfamonomethoxine to prevent intestinal infections, enhancing its antibacterial effects through synergistic action .
Pharmacokinetics and Metabolism: Studies have investigated the metabolism and pharmacokinetics of Diaveridine in food animals. In pigs, six metabolites involving O-demethylation, α-hydroxylation, and N-oxidation have been characterized. In chickens, 14 metabolites have been identified after a single oral administration, indicating extensive biotransformation in these species