| Customization: | Available |
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| CAS No.: | 17482-42-7 |
| Formula: | N/a |
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Calcium malate is a compound that pairs calcium, an essential mineral for various bodily functions, with malic acid, which is found in many fruits. It is valued for its potential health benefits and its use as a calcium supplement, particularly because it may be more easily absorbed than other forms of calcium .
Calcium malate can be prepared from bovine bones using an ultrasound-assisted method, which effectively ionizes calcium, making it more bioavailable. The optimal conditions for this preparation include a solid-liquid ratio of 1:15, a solid-acid ratio of 1:1.5, an ultrasonic power of 200 W, a temperature of 35°C, and an ultrasonication time of 17 minutes. This process achieves a calcium recovery efficiency of 66.16% and a purity of 92.54% .
Animal experiments have indicated that calcium malate derived from bovine bone can significantly increase alkaline phosphatase (ALP) activity and bone calcium content, reduce tartrate-resistant acid phosphatase (TRAP) activity, and maintain the balance of serum calcium and phosphorus. These effects suggest that calcium malate supports bone health and calcium absorption .
Calcium malate is also recognized for its potential role in improving cardiovascular health, reducing the risk of colorectal cancer, and supporting bone health by slowing bone loss in postmenopausal women . However, concerns have been raised about the safety of calcium supplementation, with some studies suggesting an increased risk of cardiovascular diseases and kidney stones with high supplemental calcium intake .
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