Atorvastatin Hemicalcium Trihydrate CAS 344423-98-9 Health Care

• Customization: Available
• Transport Package: Drum
• Specification: 99%
• Model NO.: 344423-98-9
• Origin: China
• Production Capacity: 10000kg/Month

Product Description

Product Description

 

Atorvastatin hemicalcium trihydrate CAS 344423-98-9 Health Care
 

Atorvastatin hemicalcium trihydrate is the calcium salt form of atorvastatin, which is a potent and widely prescribed statin medication. It is primarily used for the treatment of high cholesterol (hyperlipidemia) and to reduce the risk of cardiovascular disease.

Chemical Information:

• The chemical name for atorvastatin hemicalcium trihydrate is [R-(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid, calcium salt (2:1:3), trihydrate.
• The molecular formula is C66H68CaF2N4O10·3H2O, and the molecular weight is 1209.42.

Pharmacological Action: Atorvastatin works by inhibiting the enzyme HMG-CoA reductase, which is involved in the production of cholesterol in the liver. By inhibiting this enzyme, atorvastatin reduces the liver's production of cholesterol and lowers the levels of low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), and apolipoprotein B (Apo B) in the blood. It also increases the levels of high-density lipoprotein cholesterol (HDL-C), which is beneficial in managing lipid profiles.

Clinical Indications:

• It is used for the treatment of primary hypercholesterolemia, including heterozygous familial and non-familial forms, as well as mixed dyslipidemia.
• It is also indicated for the reduction of cardiovascular risk in patients with established atherosclerotic cardiovascular disease or those at high risk due to multiple risk factors.
• Additionally, it is used in patients with homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering treatments or when other means are not available.

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