| Customization: | Available |
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| Transport Package: | Drum |
| Specification: | 99% |
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Pioglitazone Hydrochloride, known by the CAS number 112529-15-4, is a medication used in the treatment of type 2 diabetes mellitus. It is part of the thiazolidinedione class of drugs, which operate by enhancing insulin sensitivity and improving glucose uptake in the body's tissues.
This drug is a selective agonist of the peroxisome proliferator-activated receptor-gamma (PPARγ), a nuclear receptor that plays a key role in the regulation of glucose and lipid metabolism. By activating PPARγ, pioglitazone increases insulin-dependent glucose disposal and reduces hepatic gluconeogenesis, leading to better blood sugar control.
Pioglitazone Hydrochloride is typically administered orally and is available in tablet form. It is often used in combination with other antidiabetic medications such as metformin or insulin when diet and exercise alone are not sufficient to control blood glucose levels. The medication has been associated with potential side effects, including fluid retention, which can exacerbate or trigger congestive heart failure, and there have been warnings about an increased risk of bladder cancer with its use
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