Diosmin CAS 520-27-4 Health Care High Quality

• Customization: Available
• Transport Package: Drum
• Specification: 99%
• Model NO.: 520-27-4
• Trademark: PUYER
• Origin: China
• Production Capacity: 10000kg/Month

Product Description

Product Description

 

Diosmin is a bioflavonoid derived from various plants, including citrus fruits, and is known for its therapeutic properties, particularly in the treatment of vascular disorders. It is commonly used to support vein and capillary function, with applications in the management of chronic venous insufficiency, hemorrhoids, and other conditions related to poor venous return.

Pharmacological Effects: Diosmin exhibits several pharmacological effects that contribute to its therapeutic use:

1. Venous Tone and Elasticity: It improves venous tone and elasticity, which can alleviate symptoms of chronic venous insufficiency.
2. Microcirculation: Diosmin enhances microcirculation, supporting better blood flow in small blood vessels.
3. Lymphatic Drainage: It promotes lymphatic drainage, which can be beneficial for conditions with edema or swelling.
4. Antioxidant Activity: Diosmin has antioxidant properties, helping to reduce oxidative stress in the body.

Pharmacokinetics: Diosmin is rapidly absorbed in the gastrointestinal tract, with a half-life ranging from 26 to 43 hours. It is metabolized in the liver and excreted primarily in the bile, with minor metabolites eliminated in the urine as glucuronic acid conjugates.

Clinical Use: Diosmin is used in clinical settings for the treatment of:

1. Chronic Venous Insufficiency (CVI): It helps reduce symptoms such as leg pain, swelling, and fatigue associated with CVI.
2. Hemorrhoids: Diosmin can alleviate symptoms during acute hemorrhoidal episodes.
3. Diabetic Complications: It has been shown to improve glucose metabolism in diabetic patients.

Safety and Tolerability: Diosmin is generally well-tolerated, with a low incidence of side effects. The most common side effects are mild gastrointestinal disturbances. It is considered safe for use over the counter and has a favorable safety profile.

 

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