Customization: | Available |
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CAS No.: | 58-32-2 |
Formula: | N/a |
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Dipyridamole, with the CAS number 58-32-2, is a pharmaceutical drug that possesses both antiplatelet and vasodilatory effects. It is a coronary vasodilator used to treat angina, as well as a platelet aggregation inhibitor that can reduce the risk of thrombosis. The chemical formula for Dipyridamole is C24H40N8O4, with a molecular weight of 504.626 . It is a yellow crystalline powder that is soluble in methanol, ethanol, and chloroform, and slightly soluble in water .
Dipyridamole works by inhibiting the enzyme phosphodiesterase, which leads to an increase in the levels of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) within cells. This results in the relaxation of smooth muscle cells and the subsequent dilation of blood vessels. Additionally, it can block the uptake of adenosine, a platelet inhibitor, by platelets and endothelial cells, thereby reducing platelet aggregation .
The drug is typically administered orally, and an intravenous formulation is also available for certain medical procedures. It is often used in combination with other antiplatelet agents like aspirin in patients who have experienced a heart attack or stroke, or those with peripheral artery disease.
Dipyridamole should be stored in a tightly closed container, protected from light, and kept at a temperature between 20-25°C (68-77°F). It is considered to be relatively safe, but side effects such as headache, dizziness, and gastrointestinal disturbances can occur. Rare but serious side effects include allergic reactions and hypotension