Customization: | Available |
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Transport Package: | Drum |
Specification: | 99% |
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Sirolimus, also known by the brand name Rapamune, is an immunosuppressive drug that is used to prevent organ rejection in patients who have undergone kidney, liver, heart, or lung transplants. It is also used to treat certain types of cancer and to prevent some complications in patients with autoimmune diseases.
Mechanism of Action: Sirolimus is a macrolide antibiotic that acts as an immunosuppressive agent by inhibiting the mammalian target of rapamycin (mTOR), a protein kinase that regulates cell growth, proliferation, and survival. By inhibiting mTOR, sirolimus suppresses the immune system's response to a transplanted organ, reducing the risk of rejection.
Indications:
Dosage and Administration: The dosage of sirolimus varies depending on the patient's weight, the type of transplant, and other factors. It is typically taken orally once daily. Blood levels of sirolimus are closely monitored to ensure therapeutic efficacy and to minimize the risk of side effects. Sirolimus is available in oral solution and tablet forms.