Diphenhydramine Hydrochloride CAS 147-24-0 Health Care High Quality

• Customization: Available
• Transport Package: Drum
• Specification: 99%
• Model NO.: 147-24-0
• Origin: China
• Production Capacity: 10000kg/Month

Product Description

Product Description

 

Diphenhydramine Hydrochloride is a first-generation antihistamine medication with the chemical name N,N-dimethyl-2-(diphenylmethoxy)ethylamine hydrochloride. It is commonly used to treat various allergic symptoms, such as skin rashes, itching, and sneezing, and is also effective in managing nausea and vomiting. Additionally, it is sometimes used as a sleep aid due to its sedative effects.

Pharmacological Effects:

• Diphenhydramine works by blocking the H1 histamine receptors in the brain, which helps to alleviate allergic reactions.
• It has a sedating effect, which can be useful for inducing sleep or reducing anxiety.

Pharmacokinetics:

• The drug is well-absorbed orally, with peak plasma concentrations occurring 2 to 4 hours after ingestion.
• It is highly protein-bound (78%-99%) and has a half-life of approximately 4 hours.
• It is metabolized in the liver and excreted primarily in the urine.

Clinical Uses:

• It is used to treat symptoms of allergies, such as hives and rashes.
• It can be used to prevent or treat motion sickness and nausea caused by various stimuli.
• Diphenhydramine is also used as a short-term sleep aid.

Safety and Precautions:

• Common side effects include drowsiness, dry mouth, and blurred vision.
• It should be used with caution in patients with glaucoma, prostate enlargement, or difficulty urinating, as it can exacerbate these conditions.
• Diphenhydramine can cause dizziness, so users should be careful when operating machinery or driving.

 

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