| Customization: | Available |
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| Transport Package: | Drum |
| Specification: | 99% |
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Clobetasol Propionate is a potent corticosteroid used to treat a variety of corticosteroid-responsive dermatoses, including moderate to severe plaque psoriasis and inflammatory and pruritic manifestations of other skin conditions. It is a prednisolone derivative with a high specificity for glucocorticoid receptors, which results in potent anti-inflammatory activity. Clobetasol propionate is available under various brand names such as Cormax, Embeline, Temovate, and Olux, and is typically applied topically as a cream, ointment, lotion, or foam.
The medication works by decreasing inflammation and immune responses in the skin. It is generally applied twice daily, and its mechanism of action includes decreased vasodilation and capillary permeability, as well as reduced leukocyte migration to sites of inflammation. The drug's effects can be seen within a few days of starting treatment, with noticeable improvements in redness, itching, and skin condition.
Clobetasol Propionate is a class I topical corticosteroid, which means it is very potent. Therefore, it should be used with caution, and treatment should not exceed two weeks to avoid the risk of side effects such as skin thinning, striae, and systemic absorption leading to hypothalamic-pituitary-adrenal (HPA) axis suppression. It is not recommended for use in children under 12 years of age, and it should not be applied to the face, underarms, or groin area, except under medical supervision.
Common side effects of Clobetasol Propionate may include skin irritation, dryness, folliculitis, and acne. More serious side effects may occur with chronic use or misuse, such as adrenal suppression, growth retardation in children, and Cushing's syndrome.
When using Clobetasol Propionate, it is important to follow the instructions provided by a healthcare professional, including the amount to be used, the areas to be treated, and the duration of treatment. Overdosage can lead to HPA axis suppression and glucocorticoid insufficiency.
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