| Customization: | Available |
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| CAS No.: | 10024-66-5 |
| Formula: | N/a |
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Manganese is an essential trace element that plays a variety of roles in the human body. It is involved in the synthesis and activation of numerous enzymes, which are crucial for various metabolic processes. Here are some of the key functions of manganese in human health:
Enzyme Activation: Manganese is a cofactor for several enzymes, including manganese superoxide dismutase (MnSOD), which is important for scavenging reactive oxygen species (ROS) and protecting cells from oxidative damage.
Bone Development: Manganese contributes to the development and maintenance of healthy bones, as it influences the synthesis of bone matrix proteins.
Glucose Metabolism: It plays a role in the regulation of glucose and lipid metabolism, which is important for individuals with conditions like diabetes.
Brain Function: Manganese is necessary for proper brain function, including the regulation of neurotransmitter synthesis and neuronal signaling.
Anti-oxidant Defense: It is involved in the body's antioxidant defense system, helping to neutralize free radicals and prevent cellular damage.
Wound Healing: Manganese is required for the healing of wounds and the regeneration of tissues.
Reproduction: It is essential for the health of reproductive tissues and the development of the fetus during pregnancy.
Energy Production: Manganese is involved in the production of adenosine triphosphate (ATP), the energy currency of cells.
Protein and Cholesterol Synthesis: It plays a role in the synthesis of proteins and cholesterol, which are vital for various cellular functions.
Manganese deficiency can lead to various health issues, including impaired bone development, reproductive problems, and irregular glucose metabolism. However, manganese toxicity can also occur, particularly with excessive exposure, which can lead to neurological issues.
It is important to maintain a balanced intake of manganese through a varied diet that includes whole grains, nuts, legumes, and leafy green vegetables. However, excessive intake should be avoided, as it can lead to health problems. The role of manganese in metabolic diseases and its interaction with oxidative stress is an area of ongoing research, with studies suggesting that both deficiency and excess can have adverse effects on health .
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