| Customization: | Available |
|---|---|
| CAS No.: | 138530-94-6 |
| Formula: | C16h14f3n3o2s |
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Product name: R-(+)-Lansoprazole
CAS No: 138530-94-6
R-(+)-Lansoprazole is an enantiomer of the proton pump inhibitor lansoprazole, which is primarily used to reduce gastric acid secretion. As a selective and potent inhibitor of the gastric H+/K+ ATPase enzyme, it effectively controls acid-related disorders. This enantiomer exhibits improved pharmacological properties and greater stability compared to its racemic counterpart, contributing to its effectiveness in treating gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.
Application and Effect
R-(+)-Lansoprazole is extensively applied in the treatment of acid-related gastrointestinal disorders. Its primary mechanism involves irreversible inhibition of the gastric proton pump (H+/K+ ATPase) in the stomach lining, thereby significantly reducing gastric acid production. This makes it highly effective in managing conditions such as gastroesophageal reflux disease (GERD), duodenal and gastric ulcers, and erosive esophagitis. Clinical studies indicate that the R-enantiomer of lansoprazole has a higher metabolic stability and longer half-life than the S-enantiomer, leading to prolonged therapeutic action and improved patient outcomes. Its enhanced pharmacokinetic profile translates into better acid suppression and potentially fewer side effects, such as reduced risk of drug interactions and adverse reactions. In addition to its therapeutic benefits, R-(+)-Lansoprazole is under investigation for its potential role in the prevention of stress-induced ulcers and as part of combination therapies for eradicating Helicobacter pylori infections. Its antioxidant and anti-inflammatory properties also contribute to mucosal healing and gastrointestinal protection, further broadening its clinical applications. Overall, R-(+)-Lansoprazole represents an advancement in proton pump inhibitor therapy, offering improved efficacy and safety profiles, particularly beneficial for patients requiring long-term acid suppression treatment.
Specifications:
| Composition | C16H14F3N3O2S |
| Assay | 99% |
| Appearance | Off-white to dark brown solid |
| CAS No. | 138530-94-6 |
| Packing | Small and bulk |
| Shelf Life | 2 years |
| Storage | Store in cool and dry area |
| Certification | ISO. |
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