| Customization: | Available |
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| CAS No.: | 352-97-6 |
| Formula: | C3h7n3o2 |
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Product name: Creatine Monohydrate + Guanidinoacetic acid
CAS No: 352-97-6
Creatine Monohydrate and Guanidinoacetic Acid (GAA) represent a synergistic duo for enhanced energy metabolism and physical performance. Creatine Monohydrate, the gold-standard sports supplement, boosts phosphocreatine stores to accelerate ATP regeneration, improving strength, power, and muscle growth. GAA, a natural precursor to creatine, further amplifies this effect by elevating the body's endogenous creatine synthesis. Together, they provide a dual-action approach: while creatine monohydrate delivers immediate bioavailable creatine, GAA supports sustained production, potentially enhancing long-term cellular energy capacity. This combination is particularly valuable for athletes, fitness enthusiasts, and individuals seeking cognitive benefits, as both compounds may also support brain function through improved energy availability. The Creatine Monohydrate + GAA combination offers a scientifically grounded, two-tiered strategy for optimizing energy metabolism, muscle performance, and recovery. By leveraging both direct creatine supplementation and its natural precursor, this pairing may provide broader and more sustained benefits than either compound alone. Ideal for athletes, aging populations, and those seeking cognitive support, it represents a next-level approach to cellular energy optimization. As with any supplement, individualized dosing and professional guidance are recommended for optimal results.
Application and Effect
Combining creatine monohydrate (CM) and guanidinoacetic acid (GAA) may offer synergistic benefits for muscle performance, energy metabolism, and overall health. Below is a breakdown of their potential applications, mechanisms, and considerations:
1. Mechanisms of Action
Creatine Monohydrate (CM):
Increases phosphocreatine (PCr) stores in muscles, enhancing ATP regeneration during high-intensity exercise.
Supports muscle growth, strength, and recovery.
May have neuroprotective and cognitive benefits.
Guanidinoacetic Acid (GAA):
A direct precursor to creatine (converted in the liver/kidneys).
May enhance endogenous creatine synthesis, especially in individuals with low dietary creatine intake.
Has been studied for improving aerobic capacity and reducing fatigue.
2. Potential Synergistic Effects
Enhanced Creatine Availability:
GAA supplementation can boost the body's creatine production, while CM provides ready-to-use creatine.
This combination may be useful for individuals with impaired creatine synthesis (e.g., certain genetic conditions).
Performance Benefits:
Anaerobic Performance (CM): Improved power output, strength, and sprint performance.
Aerobic Capacity (GAA): Some evidence suggests GAA may support endurance via creatine kinase pathways.
Health & Metabolism:
Both may help lower homocysteine (a cardiovascular risk factor).
Possible cognitive benefits due to increased brain creatine levels.
Conclusion
Combining creatine monohydrate + GAA could be beneficial for:
Maximizing creatine stores (endogenous + exogenous).
Supporting both anaerobic and aerobic performance.
Potential health benefits beyond muscle (brain, heart).
However, GAA alone may not outperform CM for strength/power goals, and proper methylation support is advised. For most athletes, CM alone is sufficient, but GAA could be a novel adjunct for specific cases.
Specifications:
| Composition | Creatine Monohydrate + Guanidinoacetic acid |
| Assay | 99% |
| Appearance | White crystalline powder |
| CAS No. | N/A |
| Packing | Small and bulk |
| Shelf Life | 2 years |
| Storage | Store in cool and dry area |
| Certification | ISO |
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