Customization: | Available |
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CAS No.: | 1483-01-8 |
Formula: | C7h17cln4o2 |
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L-Homoarginine Hydrochloride, with the CAS number 1483-01-8, is a specific inhibitor of liver-type alkaline phosphatase and has been recognized for its potential role in cardiovascular health . It is an endogenous amino acid that has been linked to various physiological functions and is increasingly being studied for its association with cardiovascular disease . L-Homoarginine is synthesized from L-arginine and glycine by the enzyme arginine:glycine amidinotransferase (AGAT), which is also involved in creatine synthesis .
As a biochemical reagent, L-Homoarginine Hydrochloride is used as an amino acid protecting group and in the pharmaceutical industry as an intermediate . It is a white crystalline powder that is soluble in water, with a molecular weight of 224.69 and a melting point ranging from 213-215°C . The compound is moisture-sensitive and should be stored under inert conditions at room temperature to maintain stability .
In the context of health, L-Homoarginine has been the subject of clinical and epidemiological studies that have revealed a strong association between low circulating levels of L-Homoarginine and cardiovascular outcomes and mortality. The structural similarity of L-Homoarginine to L-arginine suggests potential interference with L-arginine pathways, such as synthesis . However, the exact mechanisms and the role of L-Homoarginine in cardiovascular physiology and pathology require further investigation through animal experiments and clinical trials .
In summary, L-Homoarginine Hydrochloride is a significant compound in the fields of biochemistry and medicine, with applications in research, pharmaceutical development, and potential therapeutic use in cardiovascular health.