| Customization: | Available |
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| Transport Package: | Drum |
| Specification: | 99% |
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Climbazole is an antifungal agent that is commonly used in the treatment of human fungal skin infections such as dandruff and seborrheic dermatitis. It is an imidazole derivative that works by inhibiting the synthesis of ergosterol, a vital component of the fungal cell membrane. This action leads to the disruption of the cell membrane and the eventual death of the fungal cell.
Climbazole is effective against Malassezia species, which are yeasts that naturally occur on the skin and are associated with conditions like dandruff and seborrheic dermatitis. It is often found in over-the-counter (OTC) anti-dandruff and anti-fungal products, including shampoos, lotions, and conditioners.
In clinical studies, climbazole has shown to be effective in reducing symptoms of dandruff, skin redness, and itching. It is generally well-tolerated, but may cause localized skin irritation in some individuals, with symptoms such as redness, rashes, and itching.
The compound is also used as a preservative in cosmetic products due to its antifungal properties. It is considered safe for use in cosmetics, with a concentration limit set for rinse-off products and other products.
Climbazole is typically applied topically and is characterized by its ability to penetrate the skin and target the outer layers of the epidermis. Studies have investigated the influence of various solvents on the skin delivery of climbazole, with the aim of optimizing its efficacy in treating skin conditions.
In summary, climbazole is a valuable antifungal agent used in both medical and cosmetic applications, particularly for the treatment of scalp-related fungal infections. Its effectiveness and safety make it a common choice in personal care products.
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