| Customization: | Available |
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| Transport Package: | Drum |
| Specification: | 99% |
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Metformin, with the CAS number 657-24-9, is a first-line medication for the treatment of type 2 diabetes mellitus. It works by decreasing liver glucose output and increasing insulin sensitivity in muscle cells, thereby reducing blood glucose levels. Metformin is a biguanide with the chemical formula C4H11N5 and a molecular weight of 129.16 .
This oral antihyperglycemic drug is renowned for its ability to cross the blood-brain barrier and induce autophagy in the brain, which is a process of cellular renewal . It is also known to have effects beyond glycemic control, with potential benefits in cardiovascular protection, anti-tumor activity, and anti-aging .
Metformin is generally well-tolerated, with common side effects including gastrointestinal issues such as nausea, vomiting, and diarrhea. It is important to note that metformin can cause lactic acidosis, although this is rare. The medication is contraindicated in patients with renal dysfunction, liver disease, or a history of lactic acidosis .
The typical dosage of metformin starts at 500mg or 850mg once daily, with meals, and can be adjusted based on the patient's response. It is often prescribed as an extended-release formulation for better glycemic control and tolerability
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