Dl-Phenylglycine CAS 2835-06-5 Health Care High Quality

• Customization: Available
• Transport Package: Drum
• Specification: 99%
• Model NO.: 2835-06-5
• Trademark: PUYER
• Origin: China
• Production Capacity: 10000kg/Month

Product Description

Product Description

 

DL-Phenylglycine, also known as (±)-α-Aminophenylacetic acid, is a non-proteinogenic amino acid with the chemical formula C6H5CH(NH2)COOH. It is a white to faint yellow crystalline solid that is slightly soluble in water and is commonly used in the synthesis of various pharmaceuticals and as a building block in organic chemistry.

Chemical Properties:

• DL-Phenylglycine has a molecular weight of 151.16 and is characterized by its linear formula C6H5CH(NH2)COOH.
• The compound has a SMILES string of "NC(C(O)=O)c1ccccc1" and an InChI key of "ZGUNAGUHMKGQNY-UHFFFAOYSA-N".

Applications:

• It is used as a chiral building block for the synthesis of various compounds, including antibiotics, peptides, and peptide mimetic compounds.
• DL-Phenylglycine is particularly important as a side chain in the synthesis of cephalexin and ampicillin, which are widely used antibiotics.
• It has also been used in the synthesis of compounds with potential antitumor, antiviral, and neurokinin NK1 receptor antagonist activities.

Manufacturing:

• DL-Phenylglycine can be synthesized from benzaldehyde through the Strecker reaction, followed by acetylation to form the N-acetyl derivative.
• Enzymatic resolution methods, such as the use of hog kidney acylase I, can be employed to produce both D- and L-enantiomers of phenylglycine with high enantiomeric excess.

Safety and Handling:

• As with any chemical, appropriate safety measures should be taken when handling DL-Phenylglycine, including the use of personal protective equipment and proper disposal procedures.

 

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