Customization: | Available |
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CAS No.: | 56-69-9 |
Formula: | N/a |
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5-HTP 5-Hydroxytryptophan CAS 56-69-9 human nutrition high quality
5-Hydroxytryptophan (5-HTP) is a naturally occurring amino acid and a metabolic intermediate in the biosynthesis of serotonin, an important neurotransmitter in the body. It is produced from tryptophan by the action of the enzyme tryptophan hydroxylase (TPH) and is then further converted to serotonin .
5-HTP is found in some foods, such as pineapple, bananas, and certain seeds, but it is also available as a supplement, often extracted from the seeds of the African plant Griffonia simplicifolia. As a supplement, 5-HTP is used for various purposes, including as a precursor to increase serotonin levels, which can help with mood regulation, sleep improvement, and appetite control .
The physiological effects of 5-HTP have been studied in both animals and humans. It is discussed as a treatment for depression, anxiety, sleep disorders, obesity, and myoclonus. It is also considered in the context of serotonin syndrome and the potential toxic effects of impurities that might be present in supplements .
In terms of safety, 5-HTP is generally considered safe when taken in appropriate doses. However, it is advised not to take 5-HTP if you are also taking antidepressants, have liver disease, or are pregnant or breastfeeding. Side effects can include nausea, vomiting, diarrhea, and other gastrointestinal issues .
5-HTP is also being researched for its potential impact on sleep quality and gut microbiota composition, with studies suggesting it may improve certain aspects of sleep, particularly in older adults . It is important to note that while 5-HTP has shown promise in various studies, more research is needed to fully understand its effects and the appropriate dosages for different conditions.
In conclusion, 5-HTP is a significant compound in human nutrition due to its role in serotonin production, with potential benefits for mood, sleep, and weight management, but it should be used with caution and awareness of its possible interactions and side effects.