| Customization: | Available |
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| CAS No.: | 29915-38-6 |
| Formula: | N/a |
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TAPS, which stands for N-(Tris(hydroxymethyl)methyl)-3-aminopropanesulfonic acid, is a biochemical buffer known for its ability to maintain the structural integrity of biomolecules such as lysozyme under high temperatures, thus preventing thermal denaturation. It operates effectively within a pKa range that allows it to achieve half-maximal activity of protein channels at a pH of 8.1. This compound is highly soluble in water and is often used in biological research to ensure a stable pH environment for various experiments.
TAPS is particularly beneficial in the following applications:
Stabilization of Biomolecules: It serves as a stabilizing agent for proteins and other biomolecules, protecting their structure and function during experiments.
Cell Culture: TAPS is used in cell culture media to maintain a stable pH, which is essential for cell growth and metabolism.
Pharmaceutical Industry: It is utilized in the formulation of drugs to control pH levels, which is critical for drug stability and efficacy.
Protein Crystallization: TAPS can aid in the crystallization of proteins, a key technique in structural biology, by influencing protein aggregation and crystallization processes.
Biosensors: It may interact with target molecules in biosensors, leading to changes in electrical or optical properties that can be measured for detection and analysis.
In summary, TAPS is a versatile buffer with a range of uses in biological and medical research, as well as in pharmaceutical development. Its chemical properties make it suitable for creating and maintaining stable environments for a variety of scientific investigations.
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